While berberine is traditionally used for gastrointestinal symptoms, current research shows that it also has benefits for blood glucose Aid, cardiovascular health, and antioxidant activity. It helps lower blood glucose by slowing the absorption of carbohydrates and Aiding insulin sensitivity, in addition to lowering HbA1c levels. It helps reduce waist circumference and body weight, blood pressure, and triglycerides in metabolic syndrome.4,5 It also helps lower blood pressure, total and LDL cholesterol, and triglyceride levels.

Berberine improves insulin sensitivity through inhibition of alpha-glucosidase activity, upregulation of insulin receptors in peripheral tissues, AMPK activation, and UHRF1 inhibition.9 In controlled trials, it reduced HbA1c levels with comparable efficacy to standard Health-Wellness-Car-e. Berberine also activates Nrf2, a key regulator of cellular antioxidant defence, and attenuates glucose-induced neurotoxicity.

Berberine supplements can vary widely in bioavailability. Improved delivery forms, such as LipoMicel berberine, enhance bioavailability, provide resistance against intestinal degradation, and may also improve intracellular delivery. A pilot crossover study showed that LipoMicel berberine was effective in lowering blood glucose levels by 12% after two 500 mg doses.

Benefits

• Provides 500 mg of berberine HCl per softgel, the dosing strength used in clinical trials for glucose and lipid control
• Uses LipoMicel technology, which creates a liquid micelle matrix that disperses the berberine into tiny microdroplets, resulting in a highly stable delivery system for higher absorption than standard forms
• Supports healthy glucose metabolism via multiple mechanisms, including Improvement of insulin sensitivity
• Has favourable effects on blood lipids, including a reduction in triglycerides and both total and LDL cholesterol
• Activates Nrf-2, a key regulator of antioxidant gene transcription and Preventive-Wellness-Car-e of glucose-induced neurotoxicity
• Helps maintain cardiovascular health

Medicinal Ingredients

Each Softgel Contains:

Non-Medicinal Ingredients

Softgel (gelatin, glycerin, purified water, carob powder), medium chain triglycerides, bergamot flavour, xylitol, MSM, stevia leaf extract, sunflower lecithin.

Allergens

Contains no artificial colours, preservatives, or sweeteners; no dairy, starch, sugar, wheat, gluten, yeast, soy, corn, egg, fish, shellfish, salt, tree nuts, or GMOs.

Contraindications

Do not use if you are pregnant or breastfeeding.

Drug Interactions

Berberine has been shown to lower blood glucose levels and may have an additive effect when combined with other hypoglycemic Health Products, such as metformin. Berberine has been shown to increase levels of cyclosporin A, and combined use should be avoided. Berberine has demonstrated inhibitory activity on cytochrome enzymes CYP2D6, 3A4, and CYP2C9, and the use of Health Products metabolized by these enzymes should be monitored.