The data supporting the value of water-soluble pumpkin seed extract is particularly strong in studies performed in women.^7,8 Studies of aging men also demonstrated positive results.^6,9,10 The pumpkin seed has a long history of use in helping to maintain healthy bladder function.

Japanese scientists have patented a method to obtain the water-soluble constituents of the pumpkin seed, which are absorbed far more efficiently into the bloodstream. These watersoluble pumpkin seed extracts appear to be the active constituents that help with the urinary discomforts endured by so many maturing women and men.

References:
1. European urology. 2003;44(6):637-649.
2. The Journal of urology. 1986;136(5):1021-1025.
3. Journal of traditional and complementary medicine. 2014;4(1):72-74.
4. Nutrition Research and Practice. 2009;3(4):323-327.
5. British journal of urology. 1990;66(6):639-641.
6. J Med Food. 2019;22(6):551-559.
7. J Tradit Complement Med. 2019;9(2):138-142.
8. Planta Med. 2019
9. Arch Ital Urol Androl. 2016;88(2):136-43.
10. Urol Int. 2015;94(3):286-95.