Cortisol Manager 30ct by Integrative TherapeuticsIt reduces stress fast! Cortisol is a hormone activated by stress. A 28 day pilot study found that Cortisol Manager significantly reduced stress during the course of the study. In a subgroup tested for salivary cortisol levels, a drop of more than 60% was observed after the first dose, and averaged 75 83% reduction at study's end. It increases the ability to fall asleep and stay asleep without morning grogginess while providing all day stress