Nileen Riviera thinks that after getting her degree in medicine, she'd easily check off the next thing on her to-do list: Get a boyfriend. Ang kaso, walang lumalapit sa kanya. It's either intimidated sila sa kanya dahil topnotcher siya sa boards second place nga lang o kaya naman baka mahirap lang talaga siyang mahalin. That is, until the universe brings Marcus into her life. He just happens to be the guy who beat her at the board exams, which earns the very top spot in her enemies list. Niles is determined to ignore his existence, but the universe has other plans for them.