cIAP1 Ligand-Linker Conjugates 2 incorporates an IAP ligand for the E3 ubiquitin ligase, and a PROTAC linker. cIAP1 Ligand-Linker Conjugates 2 can be used to design SNIPERs.

Product information

CAS Number: 1312302-14-9

Molecular Weight: 660.80

Formula: C37H48N4O7

Chemical Name: (9H-fluoren-9-yl)methyl N-[(1S,2R)-1-{[(1S)-1-({2-[2-(2-aminoethoxy)ethoxy]ethyl}carbamoyl)-3-methylbutyl]carbamoyl}-1-hydroxy-3-phenylpropan-2-yl]carbamate

Smiles: CC(C)C[C@H](NC(=O)[C@@H](O)[C@@H](CC1=CC=CC=C1)NC(=O)OCC1C2C=CC=CC=2C2C=CC=CC=21)C(=O)NCCOCCOCCN

InChiKey: IMJARMFRGASVMW-WKNISULPSA-N

InChi: InChI=1S/C37H48N4O7/c1-25(2)22-33(35(43)39-17-19-47-21-20-46-18-16-38)40-36(44)34(42)32(23-26-10-4-3-5-11-26)41-37(45)48-24-31-29-14-8-6-12-27(29)28-13-7-9-15-30(28)31/h3-15,25,31-34,42H,16-24,38H2,1-2H3,(H,39,43)(H,40,44)(H,41,45)/t32-,33+,34+/m1/s1

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 ^oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 ^oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

Products are for research use only. Not for human use.