Phospho-alpha Synuclein (Ser129) Polyclonal Antibody

Sizes: 50µl, 100µl

Catalogue Numbers: BZ16297-50, BZ16297-100

Product: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.

Swiss-Prot: P37840

Host: Rabbit

Reactivity: Human, Mouse, Rat

Applications: WB, IHC-P

All Applications: WB: 1/500-1/1000 IHC: 1/50-1/100

Background: May be involved in the regulation of dopamine release and transport. Induces fibrillization of microtubule-associated protein tau. Reduces neuronal responsiveness to various apoptotic stimuli, leading to a decreased caspase-3 activation. Genetic alterations of SNCA resulting in aberrant polymerization into fibrils, are associated with several neurodegenerative diseases (synucleinopathies).

Purification and Purity: Affinity Purified

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: IgG

Bioworld Molecular Weight: Calculated MW: 14 kDa; Observed MW: 18 kDa

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Western blot analysis of Phospho-alpha Synuclein in mouse brain lysates using Phospho-alpha Synuclein antibody., Immunohistochemistry analysis of paraffin-embedded Human brain using Synuclein antibody. High-pressure and temperature Sodium Citrate pH 6. 0 was used for antigen retrieval. Sample with blocking peptide on the right.

Alternative Name: SNCA; NACP; PARK1; Alpha-synuclein; Non-A beta component of AD amyloid; Non-A4 component of amyloid precursor; NACP

Immunogen: Synthetic peptide of human SNCA

Conjugate: Unconjugated

Modification: Phosphorylated