MAP-4 (phospho Ser696) rabbit pAb

Sizes: 50μL, 100μL

Catalogue Numbers: ES6170-50, ES6170-100

Citations, Manuals and MSDS Available upon request.

Background: The protein encoded by this gene is a major non-neuronal microtubule-associated protein. This protein contains a domain similar to the microtubule-binding domains of neuronal microtubule-associated protein (MAP2) and microtubule-associated protein tau (MAPT/TAU). This protein promotes microtubule assembly, and has been shown to counteract destabilization of interphase microtubule catastrophe promotion. Cyclin B was found to interact with this protein, which targets cell division cycle 2 (CDC2) kinase to microtubules. The phosphorylation of this protein affects microtubule properties and cell cycle progression. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2008],

Alternate Name: MAP4; Microtubule-associated protein 4; MAP-4

Source: Rabbit

Applications: IHC; IF; ELISA

Dilution: Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/5000. Not yet tested in other applications.

Reactivity: Human; Mouse; Rat

Immunogen: The antiserum was produced against synthesized peptide derived from human MAP4 around the phosphorylation site of Ser696. AA range:662-711

Storage and Stability: -20°C/1 year

Clonality: Polyclonal

Isotype: IgG

Concentration: 1 mg/ml

Human Gene ID: 4134

Human SWISS Prot NO: P27816

Subcellular Location: Cytoplasm, cytoskeleton. Cytoplasm, cytoskeleton, microtubule organizing center. Recruitment to microtubule is inhibited by microtubules polyglutamylation.

Research Use Only