Macitentan D4 (ACT-064992 D4) is a deuterium labeled Sulfamethoxazole. Macitentan is an orally active, non-peptide dual ETA and ETB (endothelin) receptor antagonist. Macitentan has the potential for idiopathic pulmonary fibrosis (IPF) and pulmonary arterial hypertension (PAH).

Product information

CAS Number: 1258428-05-5

Molecular Weight: 592.30

Formula: C19H20Br2N6O4S

Chemical Name: {[5-(4-bromophenyl)-6-{2-[(5-bromopyrimidin-2-yl)oxy](1,1,2,2-²H₄)ethoxy}pyrimidin-4-yl]sulfamoyl}(propyl)amine

Smiles: [2H]C([2H])(OC1N=CN=C(NS(=O)(=O)NCCC)C=1C1C=CC(Br)=CC=1)C([2H])([2H])OC1=NC=C(Br)C=N1

InChiKey: JGCMEBMXRHSZKX-LZMSFWOYSA-N

InChi: InChI=1S/C19H20Br2N6O4S/c1-2-7-26-32(28,29)27-17-16(13-3-5-14(20)6-4-13)18(25-12-24-17)30-8-9-31-19-22-10-15(21)11-23-19/h3-6,10-12,26H,2,7-9H2,1H3,(H,24,25,27)/i8D2,9D2

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 ^oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 ^oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

Products are for research use only. Not for human use.