Gremlin-2 rabbit pAb

Sizes: 50μL, 100μL

Catalogue Numbers: ES8709-50, ES8709-100

Citations, Manuals and MSDS Available upon request.

Background: This gene encodes a member of the BMP (bone morphogenic protein) antagonist family. Like BMPs, BMP antagonists contain cystine knots and typically form homo- and heterodimers. The CAN (cerberus and dan) subfamily of BMP antagonists, to which this gene belongs, is characterized by a C-terminal cystine knot with an eight-membered ring. The antagonistic effect of the secreted glycosylated protein encoded by this gene is likely due to its direct binding to BMP proteins. As an antagonist of BMP, this gene may play a role in regulating organogenesis, body patterning, and tissue differentiation. [provided by RefSeq, Jul 2008],

Alternate Name: Gremlin-2 (Cysteine knot superfamily 1, BMP antagonist 2; DAN domain family member 3; Protein related to DAN and cerberus)

Source: Rabbit

Applications: WB; IHC; IF; ELISA

Dilution: WB 1:500-2000, IHC-p 1:500-200, ELISA 1:10000-20000

Reactivity: Human; Mouse

Immunogen: The antiserum was produced against synthesized peptide derived from the Internal region of human GREM2. AA range:71-120

Storage and Stability: -20°C/1 year

Clonality: Polyclonal

Isotype: IgG

Concentration: 1 mg/ml

Observed Band (KD): 19kD

Human Gene ID: 64388

Human SWISS Prot NO: Q9H772

Subcellular Location: Secreted

Research Use Only