TAT peptide (TFA) is a cell penetrating peptide (GRKKRRQRRRPQ) derived from the trans-activating transcriptional activator (Tat) from HIV-1.

Product information

Molecular Weight: 1735.92

Formula: C67H125F3N34O17

Chemical Name: glycyl-L-arginyl-L-lysyl-L-lysyl-L-arginyl-L-arginyl-L-glutaminyl-L-arginyl-L-arginyl-L-arginyl-L-prolyl-L-glutamine--2, 2, 2-trifluoroacetic acid (1/1)

Smiles: NCC(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCC(N)=O)C(O)=O.OC(=O)C(F)(F)F

InChiKey: PIRWNSGGLCUKAE-FSUPYBCYSA-N

InChi: InChI=1S/C65H124N34O15.C2HF3O2/c66-25-3-1-12-36(90-49(103)35(89-48(102)34-68)14-5-27-83-60(71)72)50(104)91-37(13-2-4-26-67)51(105)92-38(15-6-28-84-61(73)74)52(106)93-40(17-8-30-86-63(77)78)54(108)96-42(21-23-46(69)100)56(110)95-39(16-7-29-85-62(75)76)53(107)94-41(18-9-31-87-64(79)80)55(109)97-43(19-10-32-88-65(81)82)58(112)99-33-11-20-45(99)57(111)98-44(59(113)114)22-24-47(70)101;3-2(4,5)1(6)7/h35-45H,1-34,66-68H2,(H2,69,100)(H2,70,101)(H,89,102)(H,90,103)(H,91,104)(H,92,105)(H,93,106)(H,94,107)(H,95,110)(H,96,108)(H,97,109)(H,98,111)(H,113,114)(H4,71,72,83)(H4,73,74,84)(H4,75,76,85)(H4,77,78,86)(H4,79,80,87)(H4,81,82,88);(H,6,7)/t35-,36-,37-,38-,39-,40-,41-,42-,43-,44-,45-;/m0./s1

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 ^oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 ^oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

How to use

In Vitro:

TAT peptide (TFA) is a cell penetrating peptide (GRKKRRQRRRPQ) derived from the trans-activating transcriptional activator (Tat) from HIV-1. TAT peptide (TFA) (GRKKRRQRRRPQ) functionalized hybrid nanoparticles are also studied due to their combined magnetic enrichment and optical detection for cell separation and rapid cell labelling. A cell viability assay reveals good biocompatibility of these hybrid nanoparticles.

Products are for research use only. Not for human use.