SRC1 Polyclonal Antibody

Sizes: 50µl, 100µl

Catalogue Numbers: BS91280-50, BS91280-100

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Swiss-Prot: Q15788(Human)

Host: Rabbit

Reactivity: Human

Applications: WB, IHC, IP,

All Applications: WB:1:500-1:2,000
IHC:1:50-1:100

Background: Nuclear receptors for steroids, thyroid hormones and retinoic acids are ligand-dependent transcription factors that activate transcription through specific DNA binding sites in their target genes. Several related transcriptional coactivators and corepressors have been described that work in concert with the steroid receptor family to either induce or repress transcription from hormone-responsive elements. This family includes GRIP1 (for GR interacting protein 1, also designated NCoA-2 or Tif2); SRC-1 (for steroid receptor coactivator-1, also designated NCoA-1); RAC3 (also designated AIB1, for amplified in breast cancer, or ACTR), which displays elevated expression in estrogen receptor positive ovarian and breast cancers; and p/CIP (for p300/CBP/Co-Integrator Protein), which is required for the transcriptional activation of p300/CBP-dependent transcription factors

Purification and Purity: ProA affinity purified

Storage and Stability: Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

Specificity: SRC1 polyclonal antibody detects endogenous levels of SRC1 protein.

Bioworld Molecular Weight: 156 kDa

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Western blot analysis of SRC1 on K562 cell lysate using anti- SRC1 antibody at 1/2,000 dilution., Immunohistochemical analysis of paraffin-embedded human lung cancer tissue using anti-SRC1 antibody. Counter stained with hematoxylin.

Alternative Name: NCoA-1, bHLHe74, SRC-1, NCOA1, BHLHE74, SRC1, bHLHe74, Class E basic helix-loop-helix protein 74, F SRC 1, Hin 2 protein, Hin2 protein, MGC129719, MGC129720, mNRC 1, NCoA 1, NCoA-1, Ncoa1, NCOA1, Nuclear receptor coactivator 1, Nuclear receptor coactivator protein 1, NY REN 52 antigen, Protein Hin 2, Protein Hin-2, Protein Hin2, Renal carcinoma antigen NY REN 52, Renal carcinoma antigen NY-REN-52, RIP 160, RIP160, SRC 1, SRC-1, Steroid receptor coactivator 1,

Immunogen: Recombinant protein

Conjugate: Unconjugated

Modification: Unmodified