Isoliquiritigenin is a SIRT activator, GABA to-A receptor positive modulator, and inhibitor of NMDA receptors, VEGFR2, and HDACs. It increases Nrf2 expression, downregulates expression of COX-2 and PLA2 , and induces apoptosis in breast cancer cells.

Product information

CAS Number: 961-29-5

Molecular Weight: 256.25

Formula: C15H12O4

Synonym:

GU-17

4, 2', 4'-Trihydroxychalcone

Chemical Name: (E)-1-(2, 4-dihydroxyphenyl)-3-(4-hydroxyphenyl)prop-2-en-1-one

Smiles: OC1=CC(O)=CC=C1C(=O)/C=C/C1C=CC(O)=CC=1

InChiKey: DXDRHHKMWQZJHT-FPYGCLRLSA-N

InChi: InChI=1S/C15H12O4/c16-11-4-1-10(2-5-11)3-8-14(18)13-7-6-12(17)9-15(13)19/h1-9,16-17,19H/b8-3+

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Solubility: Soluble in DMSO

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 ^oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 ^oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

Products are for research use only. Not for human use.