Brexpiprazole S-oxide D8 (DM-3411 D8) is a deuterium labeled Brexpiprazole S-oxide. Brexpiprazole S-oxide is a main metabolite of Brexpiprazole and is metabolized by cytochrome P450 3A4 (CYP3A4). Brexpiprazole is an atypical antipsychotic agent and a partial agonist of human 5-HT1A and dopamine receptor with Kis of 0.12 nM and 0.3 nM, respectively. Brexpiprazole is also a 5-HT2A receptor antagonist with a Ki of 0.47 nM.

Product information

Molecular Weight: 457.61

Formula: C25H27N3O3S

Chemical Name: 7-{4-[4-(1-oxo-1λ⁴-benzothiophen-4-yl)(2,2,3,3,5,5,6,6-²H₈)piperazin-1-yl]butoxy}-1,2-dihydroquinolin-2-one

Smiles: [2H]C1([2H])N(C2C=CC=C3C=2C=CS3=O)C([2H])([2H])C([2H])([2H])N(CCCCOC2C=C3NC(=O)C=CC3=CC=2)C1([2H])[2H]

InChiKey: VJYXYAVCCLPIPM-DHNBGMNGSA-N

InChi: InChI=1S/C25H27N3O3S/c29-25-9-7-19-6-8-20(18-22(19)26-25)31-16-2-1-11-27-12-14-28(15-13-27)23-4-3-5-24-21(23)10-17-32(24)30/h3-10,17-18H,1-2,11-16H2,(H,26,29)/i12D2,13D2,14D2,15D2

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 ^oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 ^oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

Products are for research use only. Not for human use.