Semaphorin 3F Polyclonal Antibody

Sizes: 50µl, 100µl

Catalogue Numbers: BS65577-50, BS65577-100

Product: 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Swiss-Prot: Q13275

Host: Rabbit

Reactivity: Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Rabbit, Sheep,

Applications: WB,

All Applications: WB=1:500-2000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.

Background: The semaphorins are a family of proteins that are involved in signaling. All the family members have a secretion signal, a 500-amino acid sema domain, and 16 conserved cysteine residues(Kolodkin et al., 1993 [PubMed 8269517]). Sequence comparisons have grouped the secreted semaphorins into 3 general classes, all of which also have an immunoglobulin domain. The semaphorin III family, consisting of human semaphorin III (SEMA3A; MIM 603961), chicken collapsin, and mouse semaphorins A, D, and E, all have a basic domain at the C terminus. Chicken collapsin contributes to path finding by axons during development by inhibiting extension of growth cones (Luo et al., 1993 [PubMed 8402908]) through an interaction with a collapsin response mediator protein of relative molecular mass 62K (CRMP62) (Goshima et al., 1995 [PubMed7637782]), a putative homolog of an axonal guidance associated UNC33 gene product (MIM 601168). SEMA3F is a secreted member of the semaphorin III family.

Purification and Purity: affinity purified by Protein A

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: Semaphorin 3F polyclonal Antibody detects endogenous levels of Semaphorin 3F protein.

Bioworld Molecular Weight: ~88kDa

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Anti-Semaphorin 3F at 1/1000 dilution, Anti-Semaphorin 3F at 1/300 dilution, Anti-Semaphorin 3F at 1/500 dilution, Anti- Semaphorin 3F at 1/1000 dilution

Alternative Name: Semaphorin-3F; Semaphorin3F; Sema III/F; Sema IV; sema3F; SemaIII/F; SemaIV; Semaphorin IV; SemaphorinIV; SEM3F_HUMAN.

Immunogen: KLH conjugated synthetic peptide derived from human Sema3F:201-300/785

Conjugate: Unconjugated

Modification: Unmodified