PE/Cyanine5.5 Anti-Mouse CD107a/LAMP-1 Antibody [1D4B]

Sizes: 50 Tests, 100 Tests, 100 Tests×2

Catalogue Numbers: E-AB-F1254I-50, E-AB-F1254I-100, E-AB-F1254I-100×2

Citations, Manuals and MSDS Available upon request.

Abbreviation: CD107a/LAMP-1

Target Synonym: LAMP-1, Lysosome-associated membrane glycoprotein 1, lysosomal membrane glycoprotein 1, CD107 antigen-like family member A, lysosome-associated membrane protein 1,

Conjugation: PE/Cyanine5.5

Mouse

Application: FCM

Usage: Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.

Isotype: Rat IgG2a, κ

Clone No.: 1D4B

UNIProt ID: P11438

Background: The 1D4B antibody recognizes CD107a which is also known as, Lysosome-Associated Membrane Protein 1 (LAMP-1). CD107a is one of the two major glycoproteins in lysosome membranes that provide useful markers to distinguish lysosomes from other organelles. CD107a may play a role in the lysosomal degradation of certain molecules. Mouse CD107a is a type I transmembrane glycoprotein. It consists of a 40-kDa core protein which is heavily glycosylated to form heterogeneous mature glycoprotein of 110-140 kDa. It is principally expressed in epithelial cells and macrophages in a variety of organs. Following activation, CD107a is relocated to the surface of some lymphocytes, macrophages, epithelial cells, endothelial cells, platelets, and tumor cells. Cell-surface CD107a may participate in intercellular adhesion and adhesion to the extracellular matrix. Cell surface CD107a expression can serve as a useful marker for cytotoxic NK and CD8+ T cells, as well as, some malignant tumor cells.

Concentration: 5 μL/Test

Control Catalogue Number: E-AB-F09832I

Buffer: Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.

GeneID: 16783

Storage: This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze.

Shipping: Ice bag

Research Use Only