Thrombomodulin Polyclonal Antibody

Sizes: 50µl, 100µl

Catalogue Numbers: BS91345-50, BS91345-100

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Swiss-Prot: P07204(Human)

Host: Rabbit

Reactivity: Human

Applications: WB, IHC, IP,

All Applications: WB:1:500-1:2,000
IHC:1:50-1:200
IP:1:10-1:50

Background: Thrombomodulin (TM), also called CD141, is a type I membrane receptor that is specific to endothelial cells. TM has a cysteine-rich extracellular domain with six EGF-like regions. It forms a complex with Thrombin, which activates Protein C to generate activated Protein C (APC), an anticoagulant enzyme. APC together with Protein S inhibits coagulation by inactivating Factors Va and VIIIa. Deletion of the TM gene results in embryonic lethality in mice.

Purification and Purity: ProA affinity purified

Storage and Stability: Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

Specificity: Thrombomodulin polyclonal antibody detects endogenous levels of Thrombomodulin protein.

Bioworld Molecular Weight: 100 kDa

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Western blot analysis of Thrombomodulin on A431 cell using anti-Thrombomodulin antibody at 1/500 dilution., Immunohistochemical analysis of paraffin-embedded human placenta tissue using anti-Thrombomodulin antibody. Counter stained with hematoxylin.

Alternative Name: TM, THBD, THRM, AHUS 6, AHUS6, BDCA 3, BDCA3, CD 141, CD141, CD141 antigen, Fetomodulin, Thbd, THPH12, THRM, Thrombomodulin, TM, TRBM,

Immunogen: Recombinant protein

Conjugate: Unconjugated

Modification: Unmodified