Cdc7-IN-4 (compound I-C) is a potent Cdc7 kinase inhibitor extracted from patent WO2019165473A1, compound I-C. Cdc7 is a serine-threonine protein kinase enzyme which is essential for the initiation of DNA replication in the cell cycle.

Product information

CAS Number: 1402059-21-5

Molecular Weight: 479.45

Formula: C22H24F3N5O4

Chemical Name: propan-2-yl 4-hydroxy-5-{[(3Z)-3H-pyrrolo[2,3-b]pyridin-3-ylidene]methyl}-2-{[4-(2,2,2-trifluoroethyl)piperazin-1-yl]amino}furan-3-carboxylate

Smiles: CC(C)OC(=O)C1C(O)=C(/C=C2\C=NC3=NC=CC=C\23)OC=1NN1CCN(CC(F)(F)F)CC1

InChiKey: OIMZUCDSEDEUAE-GXDHUFHOSA-N

InChi: InChI=1S/C22H24F3N5O4/c1-13(2)33-21(32)17-18(31)16(10-14-11-27-19-15(14)4-3-5-26-19)34-20(17)28-30-8-6-29(7-9-30)12-22(23,24)25/h3-5,10-11,13,28,31H,6-9,12H2,1-2H3/b14-10+

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 ^oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 ^oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

Products are for research use only. Not for human use.