Bis-sulfone-PEG3-Azide is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

Product information

CAS Number: 1802908-01-5

Molecular Weight: 700.82

Formula: C33H40N4O9S2

Chemical Name: N-(2-{2-[2-(2-azidoethoxy)ethoxy]ethoxy}ethyl)-4-[3-(4-methylbenzenesulfonyl)-2-[(4-methylbenzenesulfonyl)methyl]propanoyl]benzamide

Smiles: CC1C=CC(=CC=1)S(=O)(=O)CC(CS(=O)(=O)C1C=CC(C)=CC=1)C(=O)C1C=CC(=CC=1)C(=O)NCCOCCOCCOCCN=[N+]=[N-]

InChiKey: IPFVUCCDSQHREM-UHFFFAOYSA-N

InChi: InChI=1S/C33H40N4O9S2/c1-25-3-11-30(12-4-25)47(40,41)23-29(24-48(42,43)31-13-5-26(2)6-14-31)32(38)27-7-9-28(10-8-27)33(39)35-15-17-44-19-21-46-22-20-45-18-16-36-37-34/h3-14,29H,15-24H2,1-2H3,(H,35,39)

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 ^oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 ^oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

How to use

In Vitro:

ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.

Products are for research use only. Not for human use.